It is rare for a non-profit enterprise like T-REX to co-locate venture accelerators, organizations providing grants and in-kind support services, venture capital companies, an SBA-funded resource center, and training/mentoring organizations alongside startup companies. By giving local startups the resources needed to grow and thrive in our St. Louis ecosystem, these Entrepreneur Support Organizations have brought positive energy and momentum to the City of St. Louis. The following organizations, all located in T-REX, have individually contributed to economic growth in the St. Louis region. The driving force in each case is the belief that a strong entrepreneurial ecosystem will support the creation and growth of high-growth companies and high-paying jobs. These organizations include:

Arch Grants

Arch Grants has given more than $6 million in equity-free grant money to 104 startup companies since 2012.
Through the Arch Grants Global Startup Competition, Arch Grants selects promising startups to receive $50,000 in equity-free grant money and a host of support services.  Arch Grants provides entrepreneurs with the opportunity to start a business with non-dilutive (not equity or debt) capital.  In addition, Arch Grants supports the growth of winning companies by providing free accounting, legal, marketing, web hosting, human resources, and financial consulting services.

Cultivation Capital

Cultivation Capital invests in tech startups through its IT funds and in biomedical tech startups through its Life Science fund.
Cultivation Capital is a venture capital firm that supports extraordinary entrepreneurs. This family of venture funds invest in technology, life sciences, and financial technology companies. These funds have deployed over $41 million to back 40 companies since the firm was founded in 2012, making them one of the most active seed investors in the country. Cultivation Capitals also supports and invests in multiple accelerator programs focusing on areas like financial technology, agriculture technology, cyber security technology, and women-led companies.... Find Out More Here

Cyber Up

Cyber Up is firmly grounded in our humble Midwestern values. Everything we do is for the region and without self-promotion. Our values drive mission and vision to achieve our program outputs and outcomes.
We recognize the importance for a strong regional cybersecurity workforce. There is an alarming deficit in the industry and it is critical we close the gap. Our initial solution is to offer industry specific certifications to under and unemployed individuals, to transitioning veterans, and to graduating college students from either a two-year, four-year, or post-graduation program. Looking ahead, we will develop our own cyber coursework designed to train and engage non-traditional students in the cyber industry.

IT Enrepreneur Network

ITEN is a nonprofit organization that mentors young companies. Under ITEN's mentorship, these companies have raised more than $151 million since 2006.
ITEN is a catalyst for the regional IT ecosystem, accelerating scalable tech startups with programs for rapid product development, connections to talent, networking, and access to funding.  ITEN’s offerings are designed by entrepreneurs and require neither payment nor equity from the startups. ITEN is currently assisting over 220 start-up ventures and engaging more than 70 volunteer mentors. ITEN's programs form a venture roadmap from concept through design, prototype, launch, revenue, funding and rapid scaling... Find Out More Here

Missouri SBTDC

From 2014 through 2016, the Missouri Small Business & Technology Development Centers and Missouri Procurement Technical Assistance Centers assisted clients in creating more than $2 billion in economic impact.
The Missouri Small Business & Technology Development Centers (MO SBTDC), funded by SBA and the State of Missouri, helps businesses in every stage from concept to start-up, growth to renewal, mature to succession. They provide professional business analysis, business consultations and access to technology resources. They hold educational training seminars on a variety of business topics, including: financial analysis, strategic planning, technology commercialization, management, HR, social media, marketing, taxes, customer service, business plan, start-up and more.

Network for Teaching Entrepreneurship

NFTE activates the entrepreneurial mindset and builds startup skills in youth from under-resourced communities to ensure their success and to create a more vibrant society.
Through a unique combination of high-impact student programs and exceptional teacher training and support, NFTE’s St. Louis Metro program office provides schools and partners across greater St. Louis the opportunity to change young lives through entrepreneurship. NFTE St. Louis has launched thousands of area students on their entrepreneurial journey through in-school, after-school, and summer programming.
SixThirty Logo (new version)


SixThirty provides fintech startups with up to $100K in equity funding, mentors, and connections to the top financial services companies in the country.
Backed by the St. Louis Regional Chamber and venture capital firm Cultivation Capital, SixThirty invests in eight financial-based technology startup companies each year, four for the Fall class and four to six in the spring. Those companies selected to take part in the 14-week accelerator program will receive hands-on training, mentoring, and networking opportunities with the top financial services companies in the region. Why St. Louis? St. Louis is one of the largest financial services hubs outside of New York... Find Out More Here

SixThirty CYBER

SixThirty provides cybersecurity startups with up to $250K in funding, mentors, and connections to the top cyber security-based companies in the country.
Backed by CISOs and other corporate executives and the venture capital firm Cultivation Capital, SixThirty CYBER is a business development accelerator that invests up to $250,000 in a handful of cyber security-based technology startup companies each year. The selected companies receive hands-on training, mentoring, and networking opportunities with the top CISOs and executives of regional private companies (like financial services, manufacturing, and aerospace/defense) as well as Federal Sector leaders in defense, finance & intelligence nationally.

Veterans Business Outreach Center

Our goal is to get you to the right resource(s) to help you achieve your goal. Whether that is with our Center or another agency, we are dedicated to helping you get it right.
Training is the most essential part of starting a business.  We have subject matter experts that can assist you with understanding business plans, financials, marketing, sales, human resource management, and more. We have pulled together a collection of free materials that are openly accessible around the Internet.  Let the following training pages help direct your training efforts in lieu of spending hours searching the web for information.